Die vierte Apokalypse steht kurz bevor. Was wird aus Shu und Inori?
After Mana is completely resurrected, Mana greets Shu but is shunned by him after she speaks ill of Inori, much to her anger. Gai draws out Mana's Void to fight Shu while she triggers the Fourth Apocalypse, spreading the Apocalypse virus throughout the entire world. Haruka confronts Shuichiro who commits suicide by injecting the virus into himself. Meanwhile the Undertakers fight a group of Endlaves led by Daryl, who believes he changed because of them and wants to go back to his old self. Tsugumi finds that her attempts to hack the GHQ system are being repelled by another hacker as skilled as her. Shibungi figures that the hacker is actually Kenji and after tracking his location, he kills him, allowing Tsugumi to operate freely and help Ayase defeat Daryl. Just when Shu is about to be killed by Gai, Shu is seeing a flower while hearing the Voice of Inori.
ついに始まる“四度目の黙示録”、地球上に住む全てのものに降臨する“進化”と“淘汰“の光。
幼き日からの因縁に決着をつけるべく、二人の少年は、ついに剣を交える。
傷つき倒れるシュウの前で煌く、心の雫。
――そのとき、シュウは己の罪の意味を知る。
슈는 가이의 압도적인 힘 앞에 무릎을 꿇는다.
이대로 친구들의 보이드를 끌어안은 채 최후를 맞고, 인류는 도태되는가...
모든 것을 체념한 그 때, 이노리의 목소리가 들려온다.
El cuarto apocalipsis está a la vuelta de la esquina. ¿Qué hay de Shu e Inori?
即使集及時趕到，也來不及阻止真名的復活。涯利用從真名身體中取出的虛空同集開始搏鬥，而真名卻在這個時候開始散佈失落聖誕，第四次默示錄開始了。與此同時葬儀社的眾人盡全力對抗達利爾少尉，就在涯即將給予集最後一擊的時候，集從祈的花朵中抽出了祈的虛空，終於戰勝了涯，到達了默示錄的盡頭。涯終於說出他的目的，最終為了打倒病毒而和褪去病毒的真名一起逝去。
La quarta apocalisse è pronta a illuminare con la luce dell'evoluzione e della selezione gli abitanti della Terra. I due devono risolvere la faida del passato.
Czwarta apokalipsa się rozpoczęła. Trwa ewolucja i selekcja życia na planecie. Jej dwóch mieszkańców musi rozstrzygnąć spór z przeszłości.
