Host David Yetman sets out to explore the Chihuahaun Desert and the region near the Rio Grande River in Big Bend National Park. This river defines the border between the U.S. and Mexico, and is generally considered to dissect the prettiest slice of the Chihuahaun Desert. After an informal border crossing in a rickety boat dubbed "La Enchilada," take a burro trek to visit Boquillas, one of the most remote villages in Mexico. During this trip, meet some local characters, including a veteran paleontologist who digs up deep-sea marine mammals in the middle of the desert.