Release Me chronicles the story of Texas killer Kenneth Allen McDuff who received the death sentence in 1966 for a murderous rampage that left three teen-agers dead. He was paroled years later only to kill again. His subsequent recapture and trial resulted in another death sentence, carried out in 1998. After a public outcry over his parole, there was a complete overhaul of the prison and parole systems in Texas. All told, the killer was positively linked to six murders, but it is believed that he was responsible for as many as 13 during his lifetime. Viewers gain an inside looks at the teams of prosecutors who brought him to justice and who put him on death row, not once, but twice.