Quentin Kemmer (Devon Gummersall) is a shy security guard and obsessive comic book fan who dreams of becoming a superhero like his favorite comic book character The Arachnid Avenger, and going out with his next-door neighbor Stephanie Lewis (Amelia Heinle). When his partner is killed during a botched robbery at the research laboratory where he works, Quentin is fired and he injects himself with an experimental serum derived from spiders. The next day he is wracked with a severely high fever and spends most of the day unconscious. After he recovers he discovers that he has developed increased strength.
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