Mizuki Itagaki's entertainment career began at age 10 when he was scouted in Shibuya and signed with Stardust Promotion. His breakthrough came in 2015 when he won a highly competitive audition for Solomon's Perjury, a performance that earned him the Japan Film Critics Awards' Newcomer of the Year honor. Between 2014 and 2020, Mizuki balanced his acting career with being a member of the idol group M!LK. After leaving Stardust Promotion in March 2024, Mizuki opened up about his mental health challenges in November of that year, sharing details of his hospitalization. Tragically, his family announced on April 17, 2025 that the 24-year-old had passed away. Reports indicated Mizuki had been missing since January before being found deceased in Tokyo, with authorities estimating his death occurred in early February.
