On Dec. 18, 1994, real estate millionaire Ron Rudin disappeared from his home in Las Vegas. His skull and some charred bones were found in January 1995 in the desert near Lake Mohave, about 45 miles from Las Vegas. After a two-year investigation, police moved to arrest Ron's wife, Margaret Rudin. But before they could arrest her, she went on the lam. After two years on the run, she was arrested in Massachusetts, and brought back to Las Vegas, where she stood trial for murder. Is this soft-spoken grandmother guilty of a brutal murder? 48 Hours Correspondent Harold Dow investigates.