《性敢中環》故事描述五位居住在香港中環的都市女性，呈現出當代男女的情慾交纏，女性友誼中的愛恨相織，以及職業女性所面對的苦與樂。善良可愛卻永遠不知道自己最愛是誰的韋林、說話尖酸刻薄卻又充滿知性美的網紅阿O、每晚也有新男伴的富家女Franics、能醫不自醫的心理醫生Annie和性格活潑開朗可惜從未戀愛過的幼稚園老師陽陽，性格迴異的五女之間卻早已建立了深厚的閨蜜情。五人彼此扶持，攜手度過大家在生活上遇到的種種難關。直到阿O愛上了Annie暗戀了十多年的師兄、直到Francis不理反對當上了人家的小三、直到韋林千挑萬選最後卻發現自己選錯了、直到陽陽於一夜情后懷孕不知如何是好，在她們身上所發生的一切好像都是為了要考驗她們的閨蜜情。最後發現女人的友情看似比冰塊更易碎，但原來又比鑽石更堅固。
| Season | From | To | Episodes |
|---|---|---|---|
| All Seasons | |||
| Specials | 0 | ||
| Season 1 | June 2019 | November 2019 | 12 |
| Unassigned Episodes | 0 |
| Season | From | To | Episodes |
|---|---|---|---|
| Unassigned Episodes | 12 |
| Season | From | To | Episodes |
|---|---|---|---|
| Season 1 | 0 | ||
| Unassigned Episodes | 12 |
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