Black Jack tells Dr. White to change course to the North Pole, meanwhile Renka start her plan in getting the Phoenix Disease. Later the Sky Hospital receives a call from the US Alaska base, and are told that Doctors from all the world are trying to find the cure to the Phoenix Disease, one of them being Dr. Kuma revealing that they only have 21 hours to cure or die. The National Security manager is told that they are going to launch a Nuclear Missile to rid of the Virus and as well of those ill from it. Renka gets on the Sky Hospital. Just before Renka about to shot Black Jack, her father interfere, they both shot each other, Zen Mantoku died and Renka injured badly, Black Jack decided to operate Renka, anyway. When operating Renka Black Jack finds the cure to the Phoenix Disease. The missile has been shot without any way to making it to don't crash on North Pole. While the Phoenix Disease continues to spread in Black Jack's body, he questions himself why he is saving Renka's life. He sees Benitokage, Dr. Kiriko, Dr. Honma, and his parents telling him that he did enough until he sees Pinoko in a 18 years old form telling him that the patients are waiting. The Antiserum is named Honma Antiserum . Finally Black Jack & Pinoko return with their friends, after dealing with the most dangerous "enemy" yet.
フェニックス病のウイルスを機内に蔓延させたまま、飛行を続けるスカイホスピタル。ブラック・ジャックは犠牲者が増えないよう、白拍子へ指示してSHの行き先を東京から北極へ変更させる。
Sky Hospital continúa volando mientras el virus de la enfermedad de Phoenix se propaga por todo el avión. Black Jack le indica a Shirabyoshi que cambie el destino de SH de Tokio al Polo Norte para que el número de víctimas no aumente.
