In London, sisters Yvonne and Angela tackle the dirtiest flat they have ever encountered in nearly 20 years on the job, while Maxine and her daughter Jasmine deal with a hoarder who has 20 years' worth of possessions cluttering his home. In Somerset, Shaun and his team specialise in full house clearances and they are sorting out a flat for a landlord, but the resident appears not to have thrown anything away in years and rotting household rubbish almost fills the rooms.
Shaun and his team are called out by a landlady who found her property in a very bad state, with mess over the floors, graffiti on the walls and doors pulled off their hinges. Maxine and her daughter Jasmine encounter a mountain of cigarette butts while cleaning the house of a man whose life fell apart following the breakup of his marriage, while sisters Yvonne and Angela tackle a bedsit with an infestation of German cockroaches.
Cameras follow mother and daughter Maxine and Jasmine as they face one of their biggest hoarder jobs yet - an elderly man who has a bungalow packed with 30 years' worth of belongings. Meanwhile, George and his team face a difficult clean up after a body was discovered in a flat.
Maxine and Jasmine help a man who is caring for his elderly father - the house has not had a deep-clean in decades.
Yvonne and Angela help an artist whose nine-bedroom house in Stafford is overrun with clutter, and Maxine and Jasmine go to Clacton to a maisonette that is covered in years' worth of animal fur from their 16 pets, and have three days to get it back into shape.
Yvonne and Angela try to help John, whose hoarding problem means that moving around his house in Kent is becoming increasingly difficult, while Maxine and Jasmine are in Luton to clean a neglected house for a son who cares for his mum, who suffers from a form of arthritis and is in constant pain.
Sisters Yvonne and Angela tackle a hoarder's house in Southend that is so bad the lady has been sleeping in the shed for the past six years. Plus, father-and-son team Steve and Jamie rid a drugs den of dirty needles in Newport, south Wales.
Father and Son team Steve and Jamie are called to the home of a compulsive shopper, an ex-disco dancing champion trying to cope with a mountain of purchases. Maxine and Jasmine tackle a troublesome microwave, and George and Connor have a blood biohazard clean to contend with.
In Wales, sisters Yvonne and Angela are called to a large house which was abandoned after its young owner had been struggling to cope. And in Stevenage, mum and daughter cleaning team Maxine and Jasmine tackle a house that was - until recently - home to 12 cats.
Mother and daughter cleaning team Maxine and Jasmine take on a house filled with 30 years' worth of arts and crafts materials. Yvonne and Angela tackle a flat covered in rubbish and dog mess, and ex-Army man Steve faces a shocking toilet that even he can't clean.
Maxine and Jasmine help a Dover lady who has been struggling to clean since becoming a full-time carer for her wheelchair-bound husband. In Tamworth, sisters Yvonne and Angela tackle a two-bed house for a man facing eviction because he hasn't cleaned in nearly three decades.
In Glasgow, Steve and Jamie are called to the home of a man who has been struggling since the deaths of both his partner and his best friend only a few years ago. The bedroom became a dumping ground and he's living, sleeping and eating in only one room, which is covered in rotten food, broken kitchen appliances and cigarette butts.