Roasters include Jeff Ross, Tom Arnold, Katey Sagal, Carrie Fisher, Ellen Barkin, Anthony Jeselnik, Seth Green, Amy Schumer, Wayne Brady, and Gilbert Gottfried. Sarah Chalke, Alicia Goranson, and Michael Fishman will be in attendance. Sharon Stone had been announced as one of the roasters, but dropped out for unknown reasons prior to the event.
| Name | Type | Role | |
|---|---|---|---|
| Katey Sagal | Guest Star | Roaster | |
| Jane Lynch | Guest Star | ||
| Gilbert Gottfried | Guest Star | Roaster | |
| Amy Schumer | Guest Star | Roaster | |
| Roseanne Barr | Guest Star | Roastee | |
| Seth Green | Guest Star | Roaster | |
| Tom Arnold | Guest Star | Roaster | |
| Ellen Barkin | Guest Star | Roaster | |
| Anthony Jeselnik | Guest Star | Roaster | |
| Wayne Brady | Guest Star | Roaster | |
| Jeff Ross | Guest Star | Roaster | |
| Carrie Fisher | Guest Star | Roaster |