Pat and Stoney are sent to the Ozarks to recover gold bullion stolen from the Army.
An outlaw gang is stealing gold from Chinese placer miners, then driving off their claims with outrageous taxes. Because they're Chinese, they can't sue the local government agents. With Stoney posing as a Chinese miner and Pat pretending to be a representative of an Eastern engineering company, the U.S. government tries to bring an end to the careers of the outlaw gang and crooked state government agents.
Pat and Stoney take time out from their duties to try and collect the bounty posted on a legendary golden wolf that roams the Colorado foothills. A couple of wolf hunters don't take kindly to a pair of amateur hunters horning in on their range and attempt to drive the G-Men away before they can capture or kill their quarry.
Pat and Stoney hire a pair of twins to carry secret documents and keep people confused as to who actually has the papers.
The Chippewa Indians around Lac du Flambeau are being victimized by unscrupulous lumber brokers.
An unscrupulous veterinarian starts an anthrax epidemic so he can sell serum to the ranchers for ten times it's normal cost.
Pat and Stoney are sent to help investigate a suspicious, possibly man-made malaria epidemic at a vital tungsten mine in Mexico.
Someone has leaked secret information on land needed for a railroad right-of-way and Pat and Stoney are sent to investigate.
The G-Men try to clear a cattle buyer for the government who is accused of buying stolen stock.
When the money in a bank vault is mysteriously replaced with counterfeit money, Pat and Stoney are sent to investigate.
Pat and Stoney are sent to Oklahoma to assist the state authorities to investigate a hanging judge. Stoney's plan to go undercover backfires when he is framed for murder himself.
Pat and Stoney track a killer who uses a shotgun on his victims to a town run with an iron hand by a sheriff who makes his own laws.
Pat and Stoney are assigned to investigate reports of an impostor posing as a U.S. Secret Service agent operating in Washington territory. In the guise of a government law officer, the man is shutting down all rivals of a saloon keeper's operating a crooked gambling establishment.
Pat and Stoney are ordered to break up a safe cracking gang preying on Colorado banks handling government silver bullion.
Stoney and the son of the local Indian chief are attacked while escorting a gold shipment meant for the tribe. The nuggets are stolen, the Indian killed and Stoney is arrested for the murder and theft. With his partner in jail, Pat endeavors to learn who is behind the robbery and the previous thefts of tools and supplies meant for the Indians before the tribe returns to the warpath to avenge the death of their kinsman.
Pat and Stoney are ordered to Nugget City to tear down a toll-gate on federal land. They are opposed by a woman mayor who uses the gate to keep out riff-raff and raise money for growing town's needs.