Duckman is cast in a hospital educational film with Joe Walsh; for his part he is put into a MRI chamber. The film crew is thrown out of the lab and Duckman forgotten. Left too long in the chamber, a mutation occurs which a doctor identifies as a cure for cancer. Now everyone wants Duckman's brain for their own purposes. Meanwhile, Agnes is still impersonating Grandma-ma.
| Name | Type | Role | |
|---|---|---|---|
| Michael Markowitz | Writer | ||
| Joe Walsh | Guest Star | ||
| Ron Perlman | Guest Star | ||
| Judith Light | Guest Star | ||
| Al Albert | Guest Star | ||
| Howard Storm | Guest Star | ||
| Mary Gallagher | Guest Star | ||
| Bart Flynn | Guest Star | ||
| Lauren Lane | Guest Star | ||
| Kathleen Freeman | Guest Star | ||
| Maureen McGovern | Guest Star | ||
| Eugene Levy | Guest Star | ||
| Donovan Cook | Director |