| Name | Type | Role | |
|---|---|---|---|
| George Takei | Guest Star | Self | |
| Robin Curtis | Guest Star | Self | |
| Chase Masterson | Guest Star | Self - MC | |
| Marina Sirtis | Guest Star | Self | |
| Rekha Sharma | Guest Star | Self | |
| William Shatner | Guest Star | Self | |
| Dominic Keating | Guest Star | Self | |
| Vic Mignogna | Guest Star | Self | |
| Terry Farrell | Guest Star | Self | |
| Julie Benz | Guest Star | Self | |
| Connor Trinneer | Guest Star | Self | |
| Robert Maschio | Guest Star | Self | |
| Karl Urban | Guest Star | Self | |
| Hallie Todd | Guest Star | Self | |
| Robert Beltran | Guest Star | Self | |
| Tucker Smallwood | Guest Star | Self | |
| Walter Koenig | Guest Star | Self | |
| Manu Intiraymi | Guest Star | Self | |
| Ethan Phillips | Guest Star | Self | |
| James Morrison | Guest Star | Self |