A doctor tracking venereal disease is murdered, and Five-O must track the series of encounters to find out who is a carrier. Their investigation is made doubly important by the murder of a young woman who is close to a upcoming politician. He seems a likely suspect but McGarrett suspects a deeper plot.
| Name | Type | Role | |
|---|---|---|---|
| Jerome Coopersmith | Writer | ||
| Judi Meredith | Guest Star | ||
| Robert Gleason | Guest Star | ||
| Gaye Nelson | Guest Star | ||
| Ray Buktenica | Guest Star | ||
| Robert Witthans | Guest Star | ||
| Jay Stewart | Guest Star | ||
| Ellen Blake | Guest Star | ||
| Linden Chiles | Guest Star | ||
| William Valentine | Guest Star | ||
| Electra Gailas Fair | Guest Star | ||
| Mary Frann | Guest Star | ||
| Lou Frizzell | Guest Star | ||
| Dirk Benedict | Guest Star | ||
| Ron Winston | Director |