Jimmy welcomes mean Tweets with Tom Brady, actor Jamie Dornan, TV host Robin Roberts, and a musical performance by Pentatonix.
| Name | Type | Role | |
|---|---|---|---|
| Robin Roberts | Guest Star | ||
| Mitch Grassi | Guest Star | ||
| Jamie Dornan | Guest Star | ||
| Kirstin Maldonado | Guest Star | ||
| Tom Brady | Guest Star | ||
| Kevin Olusola | Guest Star | ||
| Pentatonix | Guest Star | ||
| Matt Sallee | Guest Star | ||
| Scott Hoying | Guest Star |