Malcolms Familie bekommt neue Nachbarn. Anfangs läuft alles prima, man versteht sich blendend. Doch der Friede ist trügerisch: Bald brechen die ersten Konflikte zwischen den Kindern auf: Reese wird dauernd von der Nachbarstochter gebissen und der Nachbarsjunge erzählt Lügengeschichten über Malcolm. Während Lois wenig von ihrer Nachbarin Tina hält, werden Hal und sein neuer Nachbar Mike die dicksten Freunde - bis Malcolm und Reese ihren Rachefeldzug gegen die Neuen starten ...
Malcolm's family tries to become friendly with their new neighbours with the pool, but end up with new enemies instead. Neighbour boy Josh convinces Dewey that the lawn gnome wants to eat him, and spreads vicious lies about Malcolm that have the police coming to visit. Young daughter Emily likes to bite Reese every chance she can get, and Reese can't fight back because she's just a four-year-old girl. Lois takes an immediate dislike to Tina, the mother of the family, who refuses to admit that Emily has a biting problem and treats her Hispanic gardener like dirt. Only Hal bonds with new neighbour father Mike, but they have to carry on their friendship in secret. Malcolm enlists Reese's help in smearing Josh's name the way Josh did his. In the process of planting evidence under Josh's window they bust and draw attention to Tina having an affair, in the pool, with her gardener. The new neighbours move out. Commandant Spangler works his cadets hard to prepare for his hero, Oliver North's,
Josh, le fils des nouveaux voisins de Malcolm, convainc Dewey qu'il existe un «gnome de pelouse» et que celui-ci va le manger...
La famiglia ha dei nuovi vicini di casa, con i quali cercano di avere un buon rapporto, ma questi si rivelano i peggiori vicini che abbiano mai avuto, non la pensa invece così Hal, il quale era riuscito a trovare un buon amico nel padre di quella famiglia. All'accademia è atteso un eroe di guerra, e il comandante Spangler non vede l'ora di conoscerlo, ma finirà per ubriacarsi e perdendo così la cerimonia.
Novos vizinhos se mudam para a casa ao lado da de Malcolm e resultam ser ainda mais desagradáveis do que sua família. Na Academia Militar Marlin, Francis e o resto dos cadetes se preparam para a visita de Oliver North.
La familia se da cuenta que tienen nuevos vecinos con los cuales se llevan bien, pero al darse cuenta de como son en realidad se convierten en sus enemigos, excepto por Hal que es el único que se lleva bien con el otro jefe de la familia.
