The series revolves around four adult sisters who navigate career, romance and relationships in New York.
| Season | From | To | Episodes |
|---|---|---|---|
| All Seasons | |||
| Specials | November 1999 | 1 | |
| Season 1 | October 2005 | March 2006 | 18 |
| Unassigned Episodes | 0 |
| Name | Number of Episodes | Dates | |
|---|---|---|---|
| Lee Rose | 6 | 11/14/2005 - 03/20/2006 | |
| Joanna Kerns | 2 | 10/19/2005 - 11/07/2005 | |
| Michael Lange | 2 | 01/23/2006 - 03/06/2006 | |
| James Frawley | 1 | 10/05/2005 | |
| Jerry Levine | 1 | 12/12/2005 | |
| Patrick R. Norris | 1 | 10/26/2005 | |
| Sarah Pia Anderson | 1 | 03/20/2006 | |
| Mimi Leder | 1 | 11/30/1999 | |
| Kevin Dowling | 1 | 01/30/2006 | |
| Martha Coolidge | 1 | 02/13/2006 | |
| Arvin Brown | 1 | 10/12/2005 | |
| Elodie Keene | 1 | 10/31/2005 |
| Name | Number of Episodes | Dates | |
|---|---|---|---|
| Liz Tuccillo | 2 | 11/30/1999 - 10/05/2005 | |
| Jamie Gorenberg | 2 | 10/31/2005 - 03/06/2006 | |
| Alex Taub | 2 | 10/12/2005 - 01/30/2006 | |
| Brian Buckner | 2 | 11/14/2005 - 02/27/2006 | |
| Maggie Friedman | 2 | 10/26/2005 - 02/13/2006 | |
| Jennifer Maisel | 1 | 11/07/2005 | |
| Eric Goldberg | 1 | 03/20/2006 | |
| Marta Kauffman | 1 | 03/20/2006 | |
| Doty Abrams | 1 | 02/06/2006 | |
| Alicia Sky Varinaitis | 1 | 12/12/2005 | |
| Peter Tibbals | 1 | 03/20/2006 | |
| Ian Goldberg | 1 | 11/21/2005 | |
| Daniel J. Rubin | 1 | 01/23/2006 | |
| Bill Prady | 1 | 10/19/2005 | |
| Katherine Lingenfelter | 1 | 03/13/2006 |
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