Joe is being tracked by a relentless bounty hunter with his own vicious attack dog.
Joe comes to a Railroad Station where he's taken by the Station's Guard. There Joe uses his Army training to help the Guard who is having problems with thieves stealing from freight cars.
A fisherman discovers his nephew is constantly skipping his classes. He comes up with a plan to get him back in school but he needs Joe's help to make it happen.
As two motorcycle-riding bounty hunters chase Joe, he finds sanctuary in the bus of two missionaries.
Joe becomes the fire dog in a city where two boys, Jeff and Robbie, are setting off false fire alarms. The boys learn the hard way about what they've done, as Joe saves them from a real fire.
Joe runs into criminals at a race track.
Joe falls asleep in a barn where a little girl named Judy finds him and nurses him back to health. However, her stepfather hates dogs and wants to get rid of him so Judy runs away with Joe.
Joe sneaks in to a truck and ends up at at an animal park. He is befriended and taken in by a little boy named Tim, whose father own the dolphin act at the park. Joe becomes part of the show.
An Indian boy from the city visits his grandfather in a remote area and decides to prove his manhood by seeking out a vicious bear.
Joe rescues a boy who fell into the water, and then discovers a packet of valuable jewels on him.
After being injured in a fall, Joe is helped by a mute boy.
Joe finds Amy, a blind girl, who's gotten lost in the forest. Joe protects her and leads her to safety, and Amy in return saves him from harm.
Joe befriends an elderly antiques dealer who has purchased an old doll that a criminal is interested in.
While Joe is being chased by two hunters who mistake Joe for a vicious dog that's on the loose, he meets a backpacker named Josh McCoy, who know nothing about Joe's past, then becomes his traveling companion.
Hitchhikers Josh (Chad States) and Joe are caught up in a truck hijacking.
Joe and Josh are harassed by a pair of motorcyclists who hid a sack of stolen diamonds in Josh's backpack.
Joe searches for a prisoner who escaped from a crashed prison plane.
Joe is picked up by a dog catcher who intends to use Joe and other dogs he's captured to help him commit robberies.
While being chased by Joe, a car thief on the run tries to lure Joe into the swamp.
Josh breaks his leg and is thrown into a ditch after being hit by a camper.
Joe and Josh find work on a farm owned by a man obsessed with catching a wild stallion.
Josh meets a female hitchhiker who turns out to be a runaway.
While trying to end a 30 year feud between two men, Josh uncovers a land swindle.
Josh gets a job driving a vintage car that is later stolen by thieves who intend to strip the vehicle.
Josh gets a job as a short order cook in a cafe that is taken over by bank robbers.