When Toby rescues a young woman of a terrible car accident, he starts having disturbing visions of the son of the woman, who has gone missing. The woman is traumatized and scared for being kidnapped to gun point. As the worry for the situation of the child increases, Toby realizes that it he is going to have to act fast to find a sense to the mental discords that are tormenting him.
After receiving telepathic images of an explosion, Toby rescues his friend Vince from a fire in a block of apartments. Vince insists he didn't start the fire but has no credibility since he is a former drug addict and a meth manufacturer. As the investigation unfolds, Vince and Toby both end up on the suspect list.
One night Toby meets beautiful pathologist Mina Delia Croce in a bar and spends some time with her at her apartment. The following morning she is found dead. Toby is initially considered a suspect, but everything takes an unexpected twist when the investigation reveals that Mina might have discovered a conspiracy at her workplace.
Toby and Oz intervene in the case of Daniel, a boy from the streets who could be involved in a series of drug store burglaries. Determined to help him, Toby tries get close to him by sharing some of his personal life experience. But as Toby is approaching the truth on Daniel, he discovers that things are more complicated than he thought when Daniel's path crosses with a missing girl, Lisa Greyson, who may be in grave danger.
After Toby and Oz attend to a gunfire fight in Chinatown which leaves two dead, Toby helps Kim Chu, a blind woman whose brother Raymond is one of the murder victims. While helping Kim adjust to being alone and trying to find out who killed her brother, Toby discovers that the murder may be linked to a Chinese crime boss and that Raymond may have been involved in human smuggling.
Toby and Oz are called to a hotel after a baby falls out of a window. Before they can act, a mysterious teenage girl named Iris appears and places her hands over the baby and brings him back to life. Toby finds out she has a faith healing gift and gets a telepathic hit that makes him believe someone is trying to harm her.
Toby and Oz are called to a crime scene only to find Wade and Wendy Lassiter fatally stabbed. As Toby examines the crime scene, he telepathically senses there is someone else present, the son of the two murder victims. Toby and Detective Marks' search for the murderer is complicated in that Andy is not only deeply traumatized, but may also be suffering from a mental condition. Meanwhile, Olivia's over-bearing sister Jennifer comes for a visit and Olivia asks Toby and Oz to run interference so that the two don't end up alone together.
During dinner at Oz's parents' restaurant, Toby and Olivia learn that the family is in danger of losing the restaurant if they do not come up with $100,000 in two weeks, At first Toby tries to use his skills to win at poker without success. Through Olivia, Oz finds that a man is offering a reward of $100,000 dollars for finding his missing wife, who he has been convicted of murdering.
Arriving at the scene of an accident, Toby and Oz unsuccessfully attempt to save the victim. As he is dying, Toby telepathically sees him thinking about a young woman who Toby thinks he was trying to kill. He is backed up by the fact that a gun fell from the man's body when he and Oz picked him up off the street. Toby subsequently finds a picture of the woman on the deceased's body and he and Oz set out to find her before she becomes a murder victim.
In court, Toby and Oz' tactics are called into question after they contaminate a crime scene. While Toby is reading the thoughts of the people giving testimony, he finds out that the victim's sister may know who is responsible for her death. Toby also takes an interest in an old man he and Oz took to hospital after he was hit by a car. As he spends more time with this mysterious man, he is shocked to discover that he may hold the key to at least a part of his own mysterious past.
Toby introduces the accident victim who seems to know him to Dr. Ray, who instantly recognizes him as Frank Cardea, the man who brought Toby to him 20 years ago. As Toby continues to try to piece together Frank's fragmented memory shards, he realizes his mother is still alive and may be in mortal danger. Meanwhile, another man named Victor Cloonie appears with the benign intention of taking Toby to his mother. Toby, Oz, Olivia and Det. Marks all end up involved in the search for Maya, with potentially tragic consequences.
Toby, still haunted by guilt over the murder of his friend Detective Charlie Marks and the disappearance of his mother – has resolved to stop fighting against his mysterious gift and use his telepathic abilities to help others. When he revives a woman who nearly drowned, her amnesia gives him the perfect opportunity. As he sets out to help her remember her past, she’s also being investigated by Sgt. Michelle McCluskey of the IIB, who has taken a special interest in Toby’s connection to the woman and uncovered his more than coincidental history with a number of major criminal cases in the past.
Toby and Michelle investigate a string of high-tech thefts in Vancouver. Toby’s personal life also heats up as his relationship grows with crime reporter Tia Tremblay, who is inexplicably the one person he can’t read. Meanwhile, new director of emergency services Oz Bey realizes that being the boss is harder than he expected.
Toby and Dev investigate a serial killer who leaves live snakes with his victims, echoing the calling card of a past culprit who Michelle had previously put behind bars. Meanwhile, Michelle is trying to enjoy her maternity leave with her new baby girl and husband Adam but when her credibility is doubted with the suggestion that she may have arrested the wrong suspect, she must return to the IIB in order to save her professional reputation.
Secrets from Toby’s past are finally brought to light. Michelle, Toby, and Dev find themselves in the extremely uncomfortable position of investigating their own boss. On clandestine orders from Judge Samuel Griffin and Deputy Commissioner Earl Bamford of the IIB, the team must look into Becker’s dealings with Curtis Maynard, a disgraced former cop with connections to drug dealing.
After Toby and Oz are suddenly jolted by a defibrillator while on duty for the Integrated Investigative Bureau (IIB), Toby’s mind-reading powers are somehow transferred to Oz. While Toby uses his powers to help others, Oz takes advantage of his newfound abilities by winning at poker and trying to pick up women. But the two will have to work together to solve a tough case involving a beautiful and mysterious woman who captures Oz’s attention.
Oz and Sandy work with local reporter Missy to uncover the secret behind a “Jane Doe’s” death and the mysterious key she left behind. All clues lead to a deadly virus outbreak set to take place at a high-stakes ping pong competition.