Ren scoffs at Stimpy's dental hygiene until a toothache leads to all his teeth falling out of his head. Not even a visit from the Nerve Ending Fairy can cheer Ren up, but ever-faithful Stimpy knows a way to get Ren smiling again. / Ren and Stimpy hit the road as door-to-door Rubber Nipple Salesmen, peddling their wares to a bizarre clientele, including a psychotic Fire Chief, a paranoid Mr. Horse, and a family actually in need of new nipples!