Antimicrobial resistance is the most complex and pressing challe–‘pre-antibiotic era’ where 40% mortality is due to infections – something that is difficult to believe now. Dame Sally Davies is the Chief Medical Officer of the UK, acting as the UK government’s principal medical adviser and the professional head of all directors of public health in local government. Subscribe for regular science videos: http://bit.ly/RiSubscRibe The Ri is on Twitter: http://twitter.com/ri_science and Facebook: http://www.facebook.com/royalinstitution and Tumblr: http://ri-science.tumblr.com/ Our editorial policy: http://www.rigb.org/home/editorial-policy Subscribe for the latest science videos: http://bit.ly/RiNewsletter