The $100,000 No-Limit Hold'em Main Event is underway at the 2019 U.S. Poker Open, and just nine players remain. Chris Hunichen holds the chip lead ahead of Keith Tilston, Martin Zamani, David Peters, Jason Koon, Justin Bonomo, Sean Winter, Ryan Riess, and Nick Schulman. Only five players will finish in-the-money as four head home empty-handed in the final event of the series.
| Name | Type | Role | |
|---|---|---|---|
| Oliver 'Ali' Nejad | Host | Himself - Commentator | |
| Jamie Kerstetter | Host | Herself - Commentator | |
| Maria Ho | Host | Herself - Commentator | |
| Justin Bonomo | Guest Star | ||
| Keith Tilston | Guest Star | ||
| Sean Winter | Guest Star | ||
| Martin Zamani | Guest Star | ||
| Ryan Riess | Guest Star | ||
| David Peters | Guest Star | ||
| Nick Schulman | Guest Star | ||
| Jason Koon | Guest Star | ||
| Chris Hunichen | Guest Star |