The lives of firefighters and paramedics working for the City of Chicago Fire Department at Fire Station 51, made up of Truck 81, Squadron 3, Ambulance 61, and Battalion 25.
An emotional ride through the day-to-day chaos of the city's most explosive hospital and the courageous team of doctors that holds it together. They will tackle unique new cases inspired by topical events, forging fiery relationships in the pulse-pounding pandemonium of the emergency room, and through it all, familiar faces from the Chicago Police and Fire departments will intertwine as this third team of Chicago heroes hits the ground running.
Detective Sergeant Hank Voight and his elite Intelligence Unit at the Chicago Police Department combat atrocious offences and bring criminals to justice.