| Movie | The Bad Seed | 2018 |
| Movie | Desert's Edge | 1997 |
| Episode |
Unstable Unstable |
2023 |
| Movie | Desert's Edge | 1997 |
| Series | The Floor (US) | 2024 |
| Series | Parks and Recollection | 2021 |
| Episode |
The ’80s: Top Ten TBA |
1970 |
| Movie | I Melt with You | 2011 |
| Episode |
SmartLess Rob Lowe |
2023 |
| Episode |
The Simpsons The Very Hungry Caterpillars |
2023 |
| Episode |
The Late Late Show with James Corden Rob Lowe, Zoe Wees |
2021 |
| Episode |
The Tonight Show Starring Jimmy Fallon Rob Lowe, Lil Nas X, Regé-Jean Page, Mark Normand |
2021 |
| Episode |
Reunited Apart Wayne's World |
2020 |
| Episode |
Jimmy Kimmel Live! Rob Lowe, Danny DeVito |
2020 |
| Episode |
Jimmy Kimmel Live! Rob Lowe, Ramy Youssef, Dawes |
2020 |
| Episode |
The Talk Rob Lowe |
2020 |
| Episode |
The Late Late Show with James Corden Antonio Banderas, Rob Lowe, Kesha |
2020 |
| Episode |
What Just Happened??! with Fred Savage Flarenomenon |
2019 |
| Episode |
Jimmy Kimmel Live! Rob Lowe, Mackenzie Davis, Chris Porter |
2019 |
| Episode |
Jimmy Kimmel Live! Rob Lowe, Joey King, Catfish and the Bottlemen |
2019 |
| Episode |
Vanity Fair: Lie Detector Test Rob Lowe & Kristin Davis |
2019 |
| Episode |
The Late Late Show with James Corden Rob Lowe, Elle Fanning, Blood Orange |
2019 |
| Episode |
The Dr. Oz Show Medical Mystery: Death By Dog Lick: Are You at Risk? |
2018 |
| Episode |
The Late Late Show with James Corden Rob Lowe, Leighton Meester, Poppy |
2018 |
| Episode |
Jimmy Kimmel Live! Rob Lowe, Michelle Wolf, Jorja Smith |
2018 |
| Episode |
Hiking With Kevin Rob Lowe, The Teen Idol Thing |
2018 |
| Episode |
The Tonight Show Starring Jimmy Fallon Rob Lowe, Chrissy Metz, Fifth Harmony ft. Gucci Mane |
2017 |
| Episode |
The Orville Cupid's Dagger |
2017 |
| Episode |
Jimmy Kimmel Live! Rob Lowe, Dave Salmoni, Tom Chaplin |
2017 |
| Episode |
The Dr. Oz Show Rob Lowe- The Health Decision That Saved His Life |
2016 |
| Episode |
The Late Show with Stephen Colbert Rob Lowe, Kal Penn, Emma Willmann |
2016 |
| Episode |
Variety: Actors on Actors Episode 2 |
2016 |
| Episode |
Off Camera with Sam Jones Rob Lowe |
2016 |
| Episode |
Jimmy Kimmel Live! Rob Lowe, Chloe Bennet, Bebe Rexha |
2016 |
| Episode |
The Late Late Show with James Corden Rob Lowe, J.K. Simmons, Eliza Skinner |
2016 |
| Episode |
LIVE with Kelly and Mark Josh Groban, Rob Lowe, Will Forte |
2016 |
| Episode |
Jimmy Kimmel Live! Rob Lowe, Adrianne Palicki, Dave Gahan & Soulsavers |
2015 |
| Episode |
The Ellen DeGeneres Show Rob Lowe, Justin Bieber, Kellie Pickler, Ed Sheeran, Jamie Lawson |
2015 |
| Episode |
The Late Late Show with James Corden Rob Lowe, David Spade, Shawn Mendes |
2015 |
| Episode |
Moonbeam City Stuntstravaganza |
2015 |
| Episode |
Moonbeam City The Legend of Circuit Lake |
2015 |
| Episode |
Moonbeam City Mall Hath No Fury |
2015 |
| Episode |
Moonbeam City Lights! Camera! Reenaction! |
2015 |
| Episode |
Moonbeam City The Strike Visualizer Strikes Again |
2015 |
| Episode |
Moonbeam City Quest for Aquatica |
2015 |
| Episode |
Moonbeam City Glitzotrene : One Town’s Seduction |
2015 |
| Episode |
Moonbeam City Lasers and Liars |
2015 |
| Episode |
Moonbeam City Cop Con |
2015 |
| Episode |
Moonbeam City The Wedding of Rad (Lie) |
2015 |
| Episode |
Conan (2010) Rob Lowe, Jay Baruchel, Alingon Mitra |
2015 |
| Episode |
The Tonight Show Starring Jimmy Fallon Rob Lowe, Kat Dennings, Beth Behrs, Hozier |
2015 |
| Episode |
Real Time with Bill Maher April 11, 2014 |
2014 |
| Episode |
Today June 12, 2014 |
2014 |
| Episode |
The Late Late Show with Craig Ferguson Rob Lowe; Larry King |
2013 |
| Episode |
Late Show with David Letterman Rob Lowe; Scott Dixon; Alan Jackson |
2013 |
| Episode |
National Geographic Documentaries Killing Kennedy |
2013 |
| Episode |
Real Time with Bill Maher November 1, 2013 |
2013 |
| Episode |
Jimmy Kimmel Live! Rob Lowe; Bryce Harper; Big Boi |
2013 |
| Episode |
Jimmy Kimmel Live! Rob Lowe; Columbus Short; Nine Inch Nails |
2013 |
| Episode |
Today April 25, 2012 |
2012 |
| Episode |
Late Show with David Letterman Rob Lowe, Gov. Brian Schweitzer, The War on Drugs |
2012 |
| Episode |
Young Justice Alpha Male |
2011 |
| Episode |
The Graham Norton Show Episode 7 |
2011 |
| Episode |
Conan (2010) Return to A-Hole Acres |
2011 |
| Episode |
Californication Lawyers, Guns and Money |
2011 |
| Episode |
Parks and Recreation Freddy Spaghetti |
2010 |
| Episode |
The Tonight Show with Conan O'Brien Rob Lowe, Jane Krakowski, Hilary Hahn |
2010 |
| Episode |
Parks and Recreation The Master Plan |
2010 |
| Episode |
Family Guy Not All Dogs Go to Heaven |
2009 |
| Episode |
Friday Night with Jonathan Ross Shilpa Shetty, Alex James, Rob Lowe, CSS. |
2007 |
| Episode |
Family Guy Road to Rupert |
2007 |
| Episode |
The West Wing Transition |
2006 |
| Episode |
The Ellen DeGeneres Show Rob Lowe/Kate Walsh/Teddy Geiger |
2006 |
| Episode |
The Showbiz Show with David Spade Unknown |
2005 |
| Episode |
The Ellen DeGeneres Show Rob Lowe/Fran Drescher |
2004 |
| Episode |
The Daily Show Rob Lowe |
2003 |
| Episode |
Primetime Glick Rob Lowe / Billy Crystal |
2001 |
| Episode |
Saturday Night Live Rob Lowe/Eminem |
2000 |
| Episode |
Late Night with Conan O'Brien Rob Lowe, Michelle Williams, Hootie & The Blowfish |
1999 |
| Episode |
E! True Hollywood Story Bo Derek |
1999 |
| Episode |
E! True Hollywood Story The Brat Pack |
1999 |
| Episode |
Saturday Night Live Rob Lowe/Spice Girls |
1997 |
| Episode |
The Naked Truth The Bubble Show |
1996 |
| Episode |
The Larry Sanders Show The Bump |
1995 |
| Episode |
Great Performances Suddenly, Last Summer |
1993 |
| Episode |
Saturday Night Live Rob Lowe/The Pogues |
1990 |
| Episode |
The ABC Afterschool Special A Matter of Time |
1981 |
| Episode |
The ABC Afterschool Special Schoolboy Father |
1980 |
| Episode |
Revealed with Jules Asner Rob Lowe |
1970 |
