緝毒支隊A組組長齊雁南在潛伏打擊一個販賣毒品的犯罪團伙時突生變故。犯罪嫌疑人“黑三”的死無對證也引來檢察官林冰鐵面無私的調查。同時，為了得到一個價值連城的中醫古秘方“謎砂”，各方勢力都伸出了黑手，某大金融證劵公司總裁蘇金榮就是其一。蘇金榮既是販賣毒品團伙主謀柯世蘭的融資渠道，同時也是利益夥伴之一，因而連番出手，暗中動用秘密關係幫助柯世蘭脫身。值此風雲變幻之際，馬局長告訴齊雁南，一個有信仰的公安干警，是要同時具備韌性、抗壓性和耐性的。齊雁南和林冰在眾人的鼓勵和支持下，不畏艱難、不怕犧牲地頂住一切壓力，對犯罪分子緊追不捨。最終，在馬局長的帶領和A組同仁共同努力下，齊雁南洗刷清白並與林冰盡釋前嫌，雙方攜手共濟，將那些隱藏的，在逃的罪犯都一一捉拿歸案。
| Season | From | To | Episodes |
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| Season 1 | July 2016 | August 2016 | 41 |
| Unassigned Episodes | 0 |
| Season | From | To | Episodes |
|---|---|---|---|
| Unassigned Episodes | 41 |
| Season | From | To | Episodes |
|---|---|---|---|
| Season 1 | 0 | ||
| Unassigned Episodes | 41 |
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