"New Pharmaceuticals" include "Hot 'n' Spicy Tylenol," "L'eggs Metal Pipe Resistant Pantyhose," and "Nipsey's Own Anti-Bacterial Ointment." Regis interrupts the segment to tell Dave he's not even trying anymore. Also, during her annual Oscars special, Barbara Walters makes Dave cry.
| Name | Type | Role | |
|---|---|---|---|
| Regis Philbin | Guest Star | ||
| Plácido Domingo | Guest Star | ||
| Kevin Kline | Guest Star | ||
| Barbara Walters | Guest Star | ||
| Hal Gurnee | Director |