La série se base sur le couple central de Louis et Isabelle ainsi que sur les gens qui les entourent : le meilleur ami de Louis, François Dion (un « gars » de la construction), qu'Isabelle n'aime pas ; la meilleure amie d'Isabelle, Maryse Lemieux (psychologue), que Louis n'aime pas ; leurs voisins, Julien Champagne (professeur d'archéologie) et sa fille Gabrielle (photographe) ; les collègues de la clinique vétérinaire Dufour où travaille Louis : Paméla Lalonde (réceptionniste), Marjolaine Tremblay (technicienne), sans oublier le Dr Pascal Constantin… Au fil des saisons, d'autres personnages viendront enrichir la grande famille de 4 et demi….
| Season | From | To | Episodes |
|---|---|---|---|
| All Seasons | |||
| Specials | November 1999 | April 2001 | 2 |
| Season 1 | September 1994 | April 1995 | 30 |
| Season 2 | September 1995 | April 1996 | 30 |
| Season 3 | September 1996 | April 1997 | 26 |
| Season 4 | September 1997 | April 1998 | 27 |
| Season 5 | September 1998 | April 1999 | 27 |
| Season 6 | 28 | ||
| Season 7 | April 2001 | 25 | |
| Unassigned Episodes | 0 |
| Season | From | To | Episodes |
|---|---|---|---|
| All Seasons | |||
| Season 1 | September 1994 | April 1995 | 30 |
| Season 2 | September 1995 | April 1996 | 30 |
| Unassigned Episodes | 135 |
| Season | From | To | Episodes |
|---|---|---|---|
| Season 1 | September 1994 | September 1994 | 2 |
| Unassigned Episodes | 193 |
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