The Doctor has lost, his ageless enemy reigns supreme, and a shadow is falling over creation. Nothing can stop the devastation... except, perhaps, one woman.
| Name | Type | Role | |
|---|---|---|---|
| Russell T Davies | Writer | ||
| Amol Rajan | Guest Star | Amol Rajan | |
| Genesis Lynea | Guest Star | Harriet Arbinger | |
| Faye McKeever | Guest Star | Louise Miller | |
| Jasmine Bayes | Guest Star | Corporal Alice Sullivan | |
| Susan Twist | Guest Star | Susan Triad | |
| Aneurin Barnard | Guest Star | Roger ap Gwilliam | |
| Lenny Rush | Guest Star | Morris Gibbons | |
| Anita Dobson | Guest Star | Mrs Flood | |
| Bonnie Langford | Guest Star | Melanie Bush | |
| Tachia Newall | Guest Star | Colonel Winston Chidozie | |
| Aidan Cook | Guest Star | The Vlinx | |
| Michelle Greenidge | Guest Star | Carla Sunday | |
| Jemma Redgrave | Guest Star | Kate Lethbridge-Stewart | |
| Fela Lufadeju | Guest Star | Bailey Sinclair | |
| Nicholas Briggs | Guest Star | The Vlinx | |
| Angela Wynter | Guest Star | Cherry Sunday | |
| Yasmin Finney | Guest Star | Rose Noble | |
| Sian Clifford | Guest Star | Kind Woman | |
| Alexander Devrient | Guest Star | Colonel Christofer Ibrahim | |
| Gabriel Woolf | Guest Star | Sutekh | |
| Jamie Donoughue | Director |