Little Red Riding Hood (Anne Hathaway) discovers that the Big Bad Wolf (Patrick Warburton) has disguised himself as her grandmother. Granny (Glenn Close) jumps out of the closet tied up just as the axe-wielding woodsman (Jim Belushi) bursts through the window, startling everyone. The police quickly arrive, and Red, Wolf, Granny, and the Woodsman are questioned by Detective Nicky Flippers (David Ogden Stiers) about the events leading up to the incident.
Red Riding Hood is training in the group of Sister Hoods, when she and the Wolf are called to examine the sudden mysterious disappearance of Hansel and Gretel.