Bank robbers Seth and his paranoid brother Richard kidnap a preacher and his kids in order to sneak across the Mexican border. They end up in a topless bar, and as the dusk settles they realize that it's a home base for a gang of vampires, and that they might have to fight their way out.
Five career criminals gather in Mexico to pull off a bank heist. They soon realize that they are up against far more frightening creatures than the police pursuing them.
The prequel is set in Mexico in the early 1900s and begins with an American author, Ambrose Bierce, experiencing a nightmare in which he dies at the hands of Pancho Villa. Bierce wakes and talks to a local bartender about his intentions to join Pancho Villa's revolutionary army. He joins a stagecoach transporting a newly-wed couple, John and Mary Newlie, who are Christian mission. Meanwhile, Johnny Madrid, a dangerous local outlaw, escapes from the gallows and kidnaps his hangman's beautiful daughter, Esmeralda. Madrid receives assistance from Reece, a young woman who wants to become Madrid's apprentice as an outlaw. With the hangman and a local posse on their trail, Madrid meets with his gang. They later rob Bierce's stagecoach because of Reece's belief that Bierce possesses an invaluable object. The gang doesn't find anything of value, with Bierce claiming he is the invaluable object, as he intends to join with Pancho Villa. Annoyed by this, Madrid leaves Reece hanging in the desert. She is found by the posse who use her to track the two.
In this supernatural crime series, Seth Gecko and his violent, unpredictable brother, Richard "Richie" Gecko, are wanted by the FBI and Texas Ranger Freddie Gonzalez after a bank robbery left several people, including policemen and Gonzalez's mentor Texas Ranger Earl McGraw, dead. Heading for the Mexico border pursued by Gonzalez, the Geckos encounter former minister Jacob Fuller and his family, whom they take hostage by commandeering the Fuller's RV. Drug lord Don Carlos reroutes them to a strip club populated by vampires that all must fight until dawn in order to survive.