Nine months after the events of List of Rugrats episodes, Didi Pickles is pregnant with her second baby, which she believes will be a girl while everyone else believes it will be a boy. Didi goes into labor during her baby shower and her friends rush her to the hospital. While this is happening, the kids crawl off and explore a nursery area before being found by the other parents. When the baby is finally born after a montage of past lives, it is turns out to a boy and they name him Dil Pickles.
The Rugrats go on an adventure through the safari. Tommy impersonates Nigel Thornberry, who is his role model and spoofs his nature show. The babies' broadcast is cut short when they come across a Siberian tiger and then a crocodile, both of which threaten them. Just as they begin sinking in quicksand and are nearly attacked, this is revealed as only imagination; the babies and their families are about to go on vacation on the Lipschitz Cruise ship ship.