The film opens with newspaper photojournalist Audrey Aimes (Castle) accidentally stumbling upon a small town (Ludlow, Illinois) which has been inexplicably destroyed. All 150 people in the town are missing, and the evidence indicates they are dead. Incredibly, the local fields are also barren, as if a swarm of locusts had eaten all the crops. Aimes suspects that the military is covering something up, and travels to a nearby United States Department of Agriculture experimental farm to learn what creature might have caused the agricultural destruction. She meets Dr. Ed Wainwright (Graves), who is experimenting with radiation as a means of growing gigantic fruits and vegetables to end world hunger. Dr. Wainwright reports that there have been a number of mysterious incidents nearby, and that locusts have eaten all the radioactive wheat stored in a nearby Silo.
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