Orly's fearless 50th birthday party ends with unexpected results when her husband dies of a heart attack. Steve quits his job to join the Peace Corps. He challenges his wife Amy, who he will leave behind for a year, to find her own reason for being now that she's an empty-nester.
At Jeffrey's Irish Wake, Amy shares the news about Steve leaving her. Trish announces that she's going back to college to take all of her daughter's classes so she can continue to help her with her work. Orly, who is manic more than mourning, invites Amy to move in with her in the city.
Steve leaves for the Peace Corps. Diane, Amy's sister, invites Amy to move into the city with her instead of Orly. Diane didn't realize Amy's dog, Max, who has the same name as her new boyfriend, would be moving in as well.
Amy runs into an old friend in Central Park. Diane is conflicted by the age of her boyfriend. Trish starts school.
Amy learns that she has to return to work or possibly lose her home. Orly finally comes to terms with the loss of her husband.
Trish video chats with her daughter after seeing curious photos on her Instagram account. Amy visits with an old colleague.
Orly dreams of Jeffrey prior to attending her daughter's "Take Your Parent To Work" event along with Amy whose son works there as well.
Amy, Diane, Trish and Orly have a "Girls Night In" that involves a provocative drinking game.