A franquia inclui a série de TV Firefly e o filme Serenity. Um western de ficção científica passado 500 anos no futuro, no rescaldo de uma guerra civil universal, que se centra na tripulação rebelde de uma pequena nave espacial de transporte.
In the far-distant future, Captain Malcolm "Mal" Reynolds is a renegade former brown-coat sergeant, now turned smuggler & rogue, who is the commander of a small spacecraft, with a loyal hand-picked crew made up of the first mate, Zoe Warren; the pilot Hoban "Wash" Washburn; the gung-ho grunt Jayne Cobb; the engineer Kaylee Frye; the fugitives Dr. Simon Tam and his psychic sister River. Together, they travel the far reaches of space in search of food, money, and anything to live on.
The crew of the ship Serenity try to evade an assassin sent to recapture one of their members who is telepathic.