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Yes

Rina Hoshino as Mewtwo (voice)
Mae Whitman as Amity Blight
Glenn Close as Granny (voice)
Eric Darnell as Joe the Witch Doctor / Poacher #2 (voice)
Kotono Mitsuishi as Misato Katsuragi (voice)
Kikuko Inoue as Fuyu Kudou
Jada Pinkett Smith as Gloria (voice)
Mariah Carey as Mayor McCaskill (voice)
Romi Park as Temari (voice)
Wendy Hoopes as Quinn Morgendorffer
Edie Mirman as Telephone Recording (voice)
John Ratzenberger as P.T. Flea
Seth Rogen as Bob
John Eric Bentley as Additional Dialogue (voice) (as John Bentley)
Max Casella as Zini
Al Roker as Newscaster (voice)
Parker Goris as Flounder
Dink Trout as King of Hearts (voice)
Conner Rayburn as Little Giraffe (voice)
Kotaro Watanabe as Mewtwo (voice)
Willow Smith as Baby Glorida (voice)
Koki Uchiyama as Saku Natsusawa
Jesse McCartney as Theodore (voice)
Mami Koyama as Kei (voice)

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